⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14697151 | 0.74 | MAOA (0.31) | — | |
| SCHEMBL15049692 | 0.74 | MAOA (0.31) | — | |
| SCHEMBL25378607 | 0.74 | CYP19A1 (0.36) | — | |
| SCHEMBL15049597 | 0.74 | MAOA (0.31) | — | |
| SCHEMBL15049437 | 0.69 | CNR2 (0.35) | — | |
| SCHEMBL7228249 | 0.69 | ATM (0.30) | — | |
| SCHEMBL8938645 | 0.68 | GAA (0.34) | — | |
| SCHEMBL7922660 | 0.65 | HTR2A (0.38) | — | |
| SCHEMBL5679950 | 0.64 | HTR2A (0.50) | — | |
| SCHEMBL1117278 | 0.64 | IDO1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001590-B2 | Pyrazolopyrimidine derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| US-20200299299-A1 | NEW PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| US-10604525-B2 | Pyrazolopyrimidine derivatives | BAYAL ANIMAL HEALTH GMBH (DE) | 2020-03-31 | — | — | US | disclosed |
| US-20190071447-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-03-07 | — | — | US | disclosed |