Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMYD3 | Q9H7B4 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768853 | 0.97 | ALDH1A1 (0.59) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20768862 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20768886 | 0.93 | ALDH1A1 (0.62) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20768779 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20768756 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20768743 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20769141 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL18706453 | 0.86 | SMYD3 (0.75) | ALDH1A1HTTSMYD3LMNARAB9A | |
| SCHEMBL20768803 | 0.85 | SMYD3 (0.77) | ALDH1A1HTTSMYD3LMNAKMT2A | |
| SCHEMBL20768944 | 0.85 | ALDH1A1 (0.64) | ALDH1A1HTTSMYD3LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071416-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | SMYD3, SMYD2, EHMT1 | ALDH1A1 373/4885HTT 4168/4885SMYD3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.