Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | ST6GAL1 | P15907 | 6/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843976 | 1.00 | P2RY2 (0.57) | P2RY2TSHRGLALMNATHRB | |
| SCHEMBL20769285 | 0.91 | P2RY2 (0.58) | P2RY2TSHRGLALMNATHRB | |
| SCHEMBL4576341 | 0.91 | P2RY2 (0.66) | P2RY2P2RY6P2RY4 | |
| SCHEMBL599382 | 0.90 | P2RY2 (0.57) | P2RY2TSHRGLALMNATHRB | |
| SCHEMBL20769283 | 0.90 | P2RY2 (0.57) | P2RY2TSHRGLALMNATHRB | |
| SCHEMBL2948365 | 0.90 | P2RY2 (0.57) | P2RY2TSHRGLALMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL859799 | 0.89 | P2RY2 (0.68) | P2RY2TSHRGLALMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL28286418 | 0.89 | P2RY2 (0.68) | P2RY2TSHRGLALMNATHRB | |
| Cytarabine 5'-Phosphate SCHEMBL859797 | 0.89 | P2RY2 (0.68) | P2RY2TSHRGLALMNATHRB | |
| SCHEMBL25390040 | 0.89 | P2RY2 (0.49) | P2RY2TSHRGLALMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633663-B2 | Therapeutic strategies for ovarian cancer: AMHR2-RNA aptamer | UNIVERSITY OF CINCINNATI (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190071674-A1 | THERAPEUTIC STRATEGIES FOR OVARIAN CANCER: AMHR2-RNA APTAMER | UNIVERSITY OF CINCINNATI | 2019-03-07 | — | — | US | disclosed |