Cytarabine 5'-Phosphate

Cytarabine 5'-Phosphate

SCHEMBL859797

Nc1ccn([C@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)n1.[NaH]

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 7/20 0.68
LMNA P02545 1/20 0.67
THRB P10828 1/20 0.67
MTOR P42345 1/20 0.67
MDM2 Q00987 1/20 0.67
NCOA1 Q15788 1/20 0.67
NCOA3 Q9Y6Q9 1/20 0.67
TSHR P16473 1/20 0.66
GLA P06280 1/20 0.66
ST6GAL1 P15907 5/20 0.62
P2RY6 Q15077 3/20 0.62
P2RY4 P51582 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cytarabine 5'-Phosphate SCHEMBL859799 1.00 P2RY2 (0.68) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL28286418 1.00 P2RY2 (0.68) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL17934719 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL14669262 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL11217191 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL284602 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL6115643 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL207204 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL2681941 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2
Cytarabine 5'-Phosphate SCHEMBL16189 0.99 P2RY2 (0.69) P2RY2LMNATHRBMTORMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105213318-A Comprise the compositions of oil droplet SIGMOID PHARMA LTD 2016-01-06 CN claimed
CN-113784706-B Multi-layered pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and B vitamins, their preparation and use 菲尔若国际公司 2024-01-05 CN disclosed
CN-113784706-A Multi-layered pharmaceutical or nutraceutical solid dosage form comprising pyrimidine and/or purine derivatives and B vitamins, preparation and use thereof 菲尔若国际公司 2021-12-10 CN disclosed
CN-107737339-B Calcium phosphate-biomolecule composite material and preparation method thereof 中国科学院上海硅酸盐研究所 2021-06-15 CN disclosed
CN-109071579-B Method for producing monomer for single-stranded nucleic acid molecule 住友化学株式会社 2021-05-14 CN disclosed
EP-3450439-B1 METHOD FOR PRODUCING MONOMER FOR SINGLE-STRANDED NUCLEIC ACID MOLECULE SUMITOMO CHEMICAL CO (JP) 2021-01-20 EP disclosed
US-10308672-B2 Method for producing monomer for single-stranded nucleic acid molecule SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-06-04 US disclosed
US-20190100540-A1 METHOD FOR PRODUCING MONOMER FOR SINGLE-STRANDED NUCLEIC ACID MOLECULE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-04 US disclosed
CN-106632531-B A kind of preparation method of α -2,3 hydroxyl acetylsalicylic acid lactulose 河南科技学院 2019-02-22 CN disclosed
EP-3268027-A1 HEPCIDIN ANTAGONISTS FOR USE IN THE TREATMENT OF INFLAMMATION Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2018-01-17 EP disclosed
EP-2503997-A1 INHIBITORS OF THE PP1/GADD34 COMPLEX FOR THE TREATMENT OF A CONDITION REQUIRING AN IMMUNOSUPPRESSIVE ACTIVITY INSERM - Institut National de la Santé et de la Recherche Médicale (FR) 2012-10-03 EP disclosed
CN-102573802-A Immunomodulatory compositions comprising a polymer matrix and an oil phase SIGMOID PHARMA LTD 2012-07-11 CN disclosed
CN-102470106-A Composition comprising oil droplets SIGMOID PHARMA LTD 2012-05-23 CN disclosed
EP-2432455-A2 COMPOSITION COMPRISING OIL DROPS Sigmoid Pharma Limited (IE) 2012-03-28 EP disclosed
WO-2011098516-A1 IMPROVED COMPOSITION FOR INHIBITING TUMOR CELL PROLIFERATION IMMUNICUM AB (SE) 2011-08-18 WO disclosed
EP-2343982-A2 PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY Chiasma Inc. (US) 2011-07-20 EP disclosed
WO-2011061340-A1 INHIBITORS OF THE PP1/GADD34 COMPLEX FOR THE TREATMENT OF A CONDITION REQUIRING AN IMMUNOSUPPRESSIVE ACTIVITY INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2011-05-26 WO disclosed
WO-2010133609-A2 COMPOSITION COMPRISING OIL DROPS SIGMOID PHARMA LIMITED (IE) 2010-11-25 WO disclosed
WO-2010032140-A2 PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY CHIASMA INC. (US) 2010-03-25 WO disclosed
WO-2007139821-A2 METHODS OF USING LRR SUPERFAMILY GENES AND PROTEINS THE JOHNS HOPKINS UNIVERSITY (US) 2007-12-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308672-B2 Method for producing monomer for single-stranded nucleic acid molecule DNA2, POLM, POLRMT P2RY2 1554/4885LMNA 620/4885THRB 4064/4885
US-20190100540-A1 METHOD FOR PRODUCING MONOMER FOR SINGLE-STRANDED NUCLEIC ACID MOLECULE DNA2, POLM, POLRMT P2RY2 1554/4885LMNA 620/4885THRB 4064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.