SCHEMBL207699

SCHEMBL207699

CCCCCCCCCC(=O)CC(=O)c1cc(CCCCCCCCC)ccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.66
PPARA Q07869 1/20 0.55
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP2C8 P10632 1/20 0.54
CYP2B6 P20813 1/20 0.54
IAPP P10997 1/20 0.52
TRPV1 Q8NER1 3/20 0.52
HSD17B10 Q99714 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
GPR119 Q8TDV5 1/20 0.48
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651410 0.89 KAT8 (0.73) KAT8PPARACYP1A2CYP3A4CYP2C9
SCHEMBL15060630 0.86 KAT8 (0.69) KAT8PPARACYP3A4TRPV1HSD17B10
SCHEMBL28252921 0.86 KAT8 (0.73) KAT8PPARACYP1A2CYP3A4CYP2C9
SCHEMBL8392909 0.84 KAT8 (0.70) KAT8PPARACYP1A2CYP3A4CYP2C9
SCHEMBL29093731 0.82 KAT8 (0.63) KAT8PPARATRPV1HSD17B10MAPT
SCHEMBL28445615 0.81 KAT8 (0.79) KAT8PPARACYP1A2CYP3A4CYP2C9
SCHEMBL10826047 0.80 IAPP (0.79) KAT8PPARACYP1A2CYP3A4CYP2C9
SCHEMBL2529442 0.80 KAT8 (1.00) KAT8PPARA
SCHEMBL1373683 0.80 KAT8 (1.00) KAT8PPARA
SCHEMBL8531761 0.80 KAT8 (0.77) KAT8PPARACYP3A4IAPPTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140264166-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2014-09-18 US disclosed
US-20140264166-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2014-09-18 US disclosed
US-20140264166-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2014-09-18 US disclosed
US-20130264519-A1 Phenoxypyrazole Composition and Process for the Solvent Extraction of Metals CYTEC TECHNOLOGY CORP. 2013-10-10 US disclosed
US-20130264519-A1 Phenoxypyrazole Composition and Process for the Solvent Extraction of Metals CYTEC TECHNOLOGY CORP. 2013-10-10 US disclosed
US-20130264519-A1 Phenoxypyrazole Composition and Process for the Solvent Extraction of Metals CYTEC TECHNOLOGY CORP. 2013-10-10 US disclosed
US-8470052-B2 Phenoxypyrazole composition and process for the solvent extraction of metals CYTEC TECHNOLOGY CORP. (US) 2013-06-25 US disclosed
US-8470052-B2 Phenoxypyrazole composition and process for the solvent extraction of metals CYTEC TECHNOLOGY CORP. (US) 2013-06-25 US disclosed
EP-1926713-B1 PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECH CORP (US) 2013-04-10 EP disclosed
US-20120118109-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2012-05-17 US disclosed
US-20120118109-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2012-05-17 US disclosed
US-8088810-B2 Phenoxypyrazole composition and process for the solvent extraction of metals CYTEC TECHNOLOGY CORP. (US) 2012-01-03 US disclosed
US-8088810-B2 Phenoxypyrazole composition and process for the solvent extraction of metals CYTEC TECHNOLOGY CORP. (US) 2012-01-03 US disclosed
US-20080312452-A1 Phenoxypyrazole Composition and Process for the Solvent Extraction of Metals CYTEC TECHNOLOGY CORP. 2008-12-18 US disclosed
US-20080312452-A1 Phenoxypyrazole Composition and Process for the Solvent Extraction of Metals CYTEC TECHNOLOGY CORP. 2008-12-18 US disclosed
EP-1926713-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2008-06-04 EP disclosed
WO-2007040817-A1 PHENOXYPYRAZOLE COMPOSITION AND PROCESS FOR THE SOLVENT EXTRACTION OF METALS CYTEC TECHNOLOGY CORP. (US) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312452-A1 Phenoxypyrazole Composition and Process for the Solvent Extraction of Metals PRMT9, CHD9, CYP2C9 KAT8 323/4885PPARA 2110/4885CYP1A2 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.