Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 18/20 | 0.85 |
| ▸ | ADORA2A | P29274 | 17/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24261295 | 1.00 | ADORA2B (0.85) | ADORA2BADORA2AADORA3 | |
| SCHEMBL3661063 | 0.92 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL20784291 | 0.92 | ADORA2A (1.00) | ADORA2BADORA2A | |
| SCHEMBL20784295 | 0.92 | ADORA2A (1.00) | ADORA2BADORA2A | |
| SCHEMBL3710390 | 0.92 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL3661061 | 0.92 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL20785087 | 0.91 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL24261232 | 0.91 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL24261515 | 0.87 | ADORA2B (1.00) | ADORA2BADORA2AADORA3 | |
| SCHEMBL24261263 | 0.87 | ADORA2B (1.00) | ADORA2BADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675856-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | Corvus Pharmaceuticals, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046784-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | CORVUS PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019046784-A1 | COMPOUNDS AND METHODS FOR MODULATING ADENOSINE A2B RECEPTOR AND ADENOSINE A2A RECEPTOR | CORVUS PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |