SCHEMBL20775274

SCHEMBL20775274

Cc1cnc(/C=C/S(=O)(=O)NC(=O)Nc2c3c(cc4c2CCC4)CCC3)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20772345 0.81 NLRP3 (1.00) NLRP3
SCHEMBL20783097 0.81 NLRP3 (1.00) NLRP3
SCHEMBL20772323 0.77 NLRP3 (0.76) NLRP3
SCHEMBL20783042 0.77 NLRP3 (0.63) NLRP3
SCHEMBL20782925 0.77 NLRP3 (0.75) NLRP3
SCHEMBL20783095 0.77 NLRP3 (1.00) NLRP3
SCHEMBL20783073 0.77 NLRP3 (1.00) NLRP3
SCHEMBL20782932 0.76 NLRP3 (0.79) NLRP3
SCHEMBL20782988 0.75 NLRP3 (1.00) NLRP3
SCHEMBL20782900 0.74 NLRP3 (0.79) NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019043610-A1 NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2019-03-07 WO claimed
WO-2019043610-A1 NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2019-03-07 WO disclosed
WO-2019043610-A1 NOVEL SUBSTITUTED SULFONYLUREA DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2019-03-07 WO disclosed