Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269083 | 0.70 | KMT2A (0.62) | CRBNANO1KMT2AMEN1ROCK1 | |
| SCHEMBL1844280 | 0.70 | CRBN (0.58) | CRBNANO1KMT2AALDH1A1MEN1 | |
| SCHEMBL20777426 | 0.70 | ANO1 (0.48) | CRBNANO1KMT2AALDH1A1MEN1 | |
| SCHEMBL20777262 | 0.70 | CRBN (1.00) | CRBNANO1ALDH1A1ROCK1 | |
| SCHEMBL20773497 | 0.70 | CRBN (1.00) | CRBNANO1ALDH1A1ROCK1 | |
| SCHEMBL25875204 | 0.69 | CRBN (0.80) | CRBNANO1KMT2AMEN1ROCK1 | |
| SCHEMBL20777352 | 0.69 | ALDH1A1 (0.53) | CRBNKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL31613076 | 0.68 | PRMT5 (0.52) | CRBNANO1KMT2AALDH1A1MEN1 | |
| SCHEMBL3412231 | 0.68 | PRMT5 (0.52) | CRBNANO1KMT2AALDH1A1MEN1 | |
| SCHEMBL10467510 | 0.68 | PRMT5 (0.52) | CRBNANO1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043208-A1 | DIHYDROQUINOLINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-07 | — | — | WO | disclosed |