Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22074475 | 0.82 | TRPM8 (0.57) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL20777283 | 0.80 | TRPM8 (0.45) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL22074351 | 0.80 | TRPM8 (0.61) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL20773116 | 0.70 | TRPM8 (0.75) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL29779979 | 0.70 | TRPM8 (0.75) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL22074343 | 0.70 | TRPM8 (0.72) | KDM4EALDH1A1LMNATRPM8MAPT | |
| SCHEMBL20777359 | 0.69 | TRPM8 (0.54) | KDM4EALDH1A1LMNATRPM8MAPT | |
| SCHEMBL30579621 | 0.69 | TRPM8 (0.54) | KDM4EALDH1A1LMNATRPM8MAPT | |
| SCHEMBL30579627 | 0.67 | TRPM8 (0.51) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL29779968 | 0.67 | TRPM8 (0.74) | KDM4EALDH1A1HTTLMNATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043164-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2019-03-07 | — | — | WO | disclosed |