Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 14/20 | 0.47 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20778677 | 0.90 | HTR2A (0.54) | HTR2ASLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL20778691 | 0.90 | HTR2A (0.58) | HTR2A | |
| SCHEMBL20778620 | 0.86 | HTR2A (0.55) | HTR2A | |
| SCHEMBL20780530 | 0.85 | HTR2A (0.56) | HTR2AMBTPS1 | |
| SCHEMBL20778638 | 0.84 | HTR2A (0.51) | HTR2AMBTPS1 | |
| SCHEMBL20766516 | 0.81 | HTR2A (0.59) | HTR2ASLC6A2SLC6A4CYP2D6KCNH2 | |
| SCHEMBL20766521 | 0.80 | HTR2A (0.61) | HTR2A | |
| SCHEMBL20778718 | 0.79 | HTR2A (0.63) | HTR2ASLC6A2KCNH2SLC6A3 | |
| SCHEMBL20778610 | 0.79 | ALDH1A1 (0.47) | HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20778618 | 0.79 | HTR2A (0.61) | HTR2ASLC6A2KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040107-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |