Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256355 | 0.81 | EHMT2 (0.57) | EHMT2EHMT1APOBEC3GRAB9ANPC1 | |
| SCHEMBL5594772 | 0.80 | EHMT2 (0.42) | EHMT2EHMT1APOBEC3GRAB9ANPC1 | |
| SCHEMBL8777875 | 0.77 | EHMT2 (0.47) | EHMT2EHMT1APOBEC3GRAB9ANPC1 | |
| SCHEMBL5534216 | 0.77 | — | — | |
| SCHEMBL301719 | 0.73 | EHMT2 (0.70) | EHMT2EHMT1APOBEC3GRAB9ANPC1 | |
| SCHEMBL8309026 | 0.72 | — | — | |
| SCHEMBL2638447 | 0.72 | — | — | |
| SCHEMBL8988406 | 0.72 | — | — | |
| SCHEMBL10793039 | 0.72 | — | — | |
| SCHEMBL11088703 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163481-B2 | Of nucleoproteins containing histones by lysis in solution comprising enzyme-inhibitory concentration of chaotropic reagent | University of Pittsburgh - of the Commonwealth Systems of Higher Education (US) | 2012-04-24 | — | — | US | claimed |
| US-20080241845-A1 | Method of Extracting Chromatin Fractions From Intact Cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-02 | — | — | US | claimed |
| US-8163481-B2 | Of nucleoproteins containing histones by lysis in solution comprising enzyme-inhibitory concentration of chaotropic reagent | University of Pittsburgh - of the Commonwealth Systems of Higher Education (US) | 2012-04-24 | — | — | US | disclosed |
| US-20080241845-A1 | Method of Extracting Chromatin Fractions From Intact Cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-02 | — | — | US | disclosed |
| US-6069144-A | N-heterocyclic compounds, intermediate products used to prepare them, agents containing them and their use in antifungal applications | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-30 | — | — | US | disclosed |