SCHEMBL6256355

SCHEMBL6256355

CC[CH]SSc1ccccn1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.57
EHMT1 Q9H9B1 1/20 0.57
APOBEC3G Q9HC16 1/20 0.57
RAB9A P51151 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 5/20 0.38
KMT2A Q03164 4/20 0.38
HPGD P15428 3/20 0.38
MEN1 O00255 3/20 0.38
MAPT P10636 3/20 0.38
ICAM1 P05362 1/20 0.38
SELE P16581 1/20 0.38
VCAM1 P19320 1/20 0.38
USP2 O75604 1/20 0.38
GAA P10253 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2077933 0.81 EHMT2 (0.50) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL19743385 0.79 EHMT2 (0.64) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL30195130 0.76 EHMT2 (0.59) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL28579828 0.76 EHMT2 (0.59) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL423720 0.76 EHMT2 (0.59) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
Methyl Alcohol SCHEMBL28484914 0.75 EHMT2 (0.90) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL29349787 0.75 EHMT2 (1.00) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL27972393 0.75 EHMT2 (1.00) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
SCHEMBL21174 0.75 EHMT2 (1.00) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1
Ethylamine SCHEMBL18229941 0.75 EHMT2 (0.71) EHMT2EHMT1APOBEC3GRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3031447-B1 NUCLEIC ACID-ENCAPSULATING POLYMER MICELLE COMPLEX AND METHOD FOR PRODUCING SAME JAPAN SCIENCE & TECH AGENCY (JP) 2019-12-25 EP disclosed
US-20160184457-A1 NUCLEIC ACID-ENCAPSULATING POLYMER MICELLE COMPLEX AND METHOD FOR PRODUCING SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2016-06-30 US disclosed
EP-3031447-A1 NUCLEIC ACID-ENCAPSULATING POLYMER MICELLE COMPLEX AND METHOD FOR PRODUCING SAME Japan Science and Technology Agency (JP) 2016-06-15 EP disclosed
EP-0786006-B1 CEPHALOSPORIN C AMIDOHYDROLASE, PRODUCTION AND USE GLAXO GROUP LTD (GB) 2005-09-28 EP disclosed
WO-2002083951-A1 MULTIPLEXED LIGAND/PROTEIN BINDING ASSAYS WITH PNA LABELS NORTHEASTERN UNIVERSITY (US) 2002-10-24 WO disclosed
US-6297032-B1 EXPRESSING ENZYME ASSOCIATED WITH THE DEGRADATION OF PREFERENTIAL ANTIBIOTIC; TRANSFORM AND CULTURE CELLS, RECOVER PREFERENTIAL PROTEIN GLAXO GROUP LIMITED (GB) 2001-10-02 US disclosed
US-5919648-A ONE STEP CONVERSION OF CEPHALOSPORIN C OR DERIVATIVE INTO 7-AMINOCEPHALOSPORANIC ACID OR DERIVATIVE USING AMINOHYDROLASE FROM PSUEDOMONAS VESICULARIS B965; FOR CEPHALOTHIN, CEPHALORIDINE, AND CEFUROXIME SYNTHESIS GLAXO GROUP LIMITED (GB) 1999-07-06 US disclosed
EP-0786006-A2 CEPHALOSPORIN C AMIDOHYDROLASE, PRODUCTION AND USE GLAXO GROUP LIMITED (GB) 1997-07-30 EP disclosed
WO-1996016174-A2 CEPHALOSPORIN C AMIDOHYDROLASE, PRODUCTION AND USE GLAXO GROUP LIMITED (GB) 1996-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160184457-A1 NUCLEIC ACID-ENCAPSULATING POLYMER MICELLE COMPLEX AND METHOD FOR PRODUCING SAME POLM, DNA2, POLRMT EHMT2 2263/4885EHMT1 2821/4885APOBEC3G 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.