Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812414 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL8427465 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL5594776 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL3955037 | 0.83 | — | — | |
| SCHEMBL7208033 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4686394 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4686390 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL5020551 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL5185156 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL3182706 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163481-B2 | Of nucleoproteins containing histones by lysis in solution comprising enzyme-inhibitory concentration of chaotropic reagent | University of Pittsburgh - of the Commonwealth Systems of Higher Education (US) | 2012-04-24 | — | — | US | claimed |
| US-20080241845-A1 | Method of Extracting Chromatin Fractions From Intact Cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-02 | — | — | US | claimed |
| US-8163481-B2 | Of nucleoproteins containing histones by lysis in solution comprising enzyme-inhibitory concentration of chaotropic reagent | University of Pittsburgh - of the Commonwealth Systems of Higher Education (US) | 2012-04-24 | — | — | US | disclosed |
| US-20080241845-A1 | Method of Extracting Chromatin Fractions From Intact Cells | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-02 | — | — | US | disclosed |
| CN-1070488-C | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-09-05 | — | — | CN | disclosed |
| EP-0706523-B1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-01-24 | — | — | EP | disclosed |
| US-6069144-A | N-heterocyclic compounds, intermediate products used to prepare them, agents containing them and their use in antifungal applications | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-30 | — | — | US | disclosed |
| US-5942641-A | TREATMENT OF ALZHEIMER'S DISEASE, NERVOUS SYSTEM DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5859030-A | Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-01-12 | — | — | US | disclosed |
| EP-0655992-B1 | FLUORENONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CENTRAL OR PERIPHERAL NERVE DEGENERATION REPAIR AND PROTECTIVE AGENT | OTSUKA PHARMA CO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5773451-A | BACTERICIDES FOR HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-06-30 | — | — | US | disclosed |
| WO-1996000224-A1 | 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995034554-A1 | SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-12-21 | — | — | WO | disclosed |
| EP-0678500-A1 | Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |
| EP-0655992-A1 | FLUORENONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CENTRAL OR PERIPHERAL NERVE DEGENERATION REPAIR AND PROTECTIVE AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| WO-1995001351-A1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-01-12 | — | — | WO | disclosed |
| WO-1995000468-A1 | FLUORENONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CENTRAL OR PERIPHERAL NERVE DEGENERATION REPAIR AND PROTECTIVE AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-05 | — | — | WO | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |