Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | AXL | P30530 | 7/20 | 0.46 |
| ▸ | MERTK | Q12866 | 2/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 6/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901795 | 0.91 | BRD4 (0.55) | TTKMAPK8BRD4AXLMERTK | |
| SCHEMBL20766946 | 0.91 | BRD4 (0.55) | TTKMAPK8BRD4AXLMERTK | |
| SCHEMBL20779658 | 0.77 | AXL (0.49) | TTKMAPK8AXLMERTKTYRO3 | |
| SCHEMBL20766987 | 0.72 | BRD4 (0.54) | BRD4 | |
| SCHEMBL29901808 | 0.72 | BRD4 (0.54) | BRD4 | |
| SCHEMBL20384218 | 0.72 | BRD4 (0.86) | BRD4 | |
| SCHEMBL20384186 | 0.72 | BRD4 (0.86) | BRD4 | |
| SCHEMBL20384543 | 0.72 | BRD4 (0.86) | BRD4 | |
| SCHEMBL29901813 | 0.72 | BRD4 (0.56) | BRD4IRAK1IRAK4 | |
| SCHEMBL20766196 | 0.72 | BRD4 (0.56) | BRD4IRAK1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |