Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766987 | 1.00 | BRD4 (0.54) | BRD4PTGS2PTGS1YAP1 | |
| SCHEMBL20767361 | 0.89 | BRD4 (0.43) | BRD4YAP1 | |
| SCHEMBL20766196 | 0.84 | BRD4 (0.56) | BRD4PTGS2PTGS1YAP1 | |
| SCHEMBL29901813 | 0.84 | BRD4 (0.56) | BRD4PTGS2PTGS1YAP1 | |
| SCHEMBL20766946 | 0.81 | BRD4 (0.55) | BRD4PTGS2 | |
| SCHEMBL29901795 | 0.81 | BRD4 (0.55) | BRD4PTGS2 | |
| SCHEMBL20767240 | 0.80 | BRD4 (0.52) | BRD4PTGS2PTGS1YAP1 | |
| SCHEMBL20779812 | 0.80 | OPRK1 (0.38) | BRD4 | |
| SCHEMBL25781538 | 0.76 | BRD4 (0.54) | BRD4PTGS2PTGS1YAP1 | |
| SCHEMBL20779647 | 0.74 | KDM1A (0.52) | BRD4PTGS2PTGS1YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |