Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23127120 | 0.95 | MAPT (0.52) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL25945989 | 0.95 | MAPT (0.52) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL25949518 | 0.95 | MAPT (0.52) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL23127122 | 0.95 | MAPT (0.52) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL20779501 | 0.93 | MAOB (0.47) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL19351506 | 0.93 | MAPT (0.46) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL19351667 | 0.93 | LMNA (0.50) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL24771884 | 0.93 | LMNA (0.50) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL19351669 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL19351505 | 0.90 | MAPT (0.45) | MAPTSMN1; SMN2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046271-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |