Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779666 | 1.00 | YAP1 (0.36) | YAP1ALOX15ABCC1HDAC8IDO1 | |
| SCHEMBL20779858 | 0.98 | YAP1 (0.36) | YAP1ALOX15ABCC1HDAC8IDO1 | |
| SCHEMBL20779601 | 0.91 | CHEK1 (0.33) | YAP1ALOX15 | |
| SCHEMBL20779749 | 0.90 | YAP1 (0.35) | YAP1MAPT | |
| SCHEMBL20779745 | 0.89 | YAP1 (0.32) | YAP1 | |
| SCHEMBL20779546 | 0.89 | YAP1 (0.37) | YAP1ALOX15HDAC8IDO1MAPT | |
| SCHEMBL20779783 | 0.88 | YAP1 (0.31) | YAP1 | |
| SCHEMBL20779740 | 0.87 | YAP1 (0.31) | YAP1 | |
| SCHEMBL20779804 | 0.87 | SMN1; SMN2 (0.34) | YAP1ALOX15IDO1MAPTKDM4E | |
| SCHEMBL20779561 | 0.86 | YAP1 (0.38) | YAP1ALOX15HDAC8IDO1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |