Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.50 |
| ▸ | YAP1 | P46937 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 6/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 6/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20779436 | 0.86 | TEAD1 (0.66) | TEAD1YAP1ABL1BCRTLR2 | |
| SCHEMBL29901814 | 0.81 | TEAD1 (0.77) | TEAD1YAP1TLR2TLR1 | |
| SCHEMBL20767405 | 0.81 | TEAD1 (0.77) | TEAD1YAP1TLR2TLR1 | |
| SCHEMBL20779641 | 0.75 | CYP2C19 (0.40) | PDE3BPDE3ACYP2E1CYP3A4CYP2A6 | |
| SCHEMBL20779733 | 0.74 | DYRK1A (0.42) | TEAD1YAP1ABL1BCRAKR1C3 | |
| SCHEMBL24790230 | 0.73 | TEAD1 (0.50) | TEAD1YAP1 | |
| SCHEMBL25097457 | 0.73 | TEAD1 (0.48) | TEAD1YAP1ACP1 | |
| SCHEMBL24791423 | 0.73 | TEAD1 (0.50) | TEAD1YAP1 | |
| SCHEMBL20779628 | 0.72 | KAT6A (0.34) | PDE3BPDE3ACYP2E1CYP3A4CYP2A6 | |
| SCHEMBL25877124 | 0.72 | TEAD1 (0.71) | TEAD1YAP1ABL1BCRTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040380-A1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-02-28 | — | — | WO | disclosed |