Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.77 |
| ▸ | YAP1 | P46937 | 1/20 | 0.77 |
| ▸ | TNNI3K | Q59H18 | 10/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767405 | 1.00 | TEAD1 (0.77) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL29901779 | 0.90 | TEAD1 (0.62) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL20767446 | 0.90 | TEAD1 (0.62) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL20779435 | 0.87 | TEAD1 (1.00) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL29438871 | 0.87 | TEAD1 (1.00) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL20779719 | 0.83 | TEAD1 (0.74) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL20779671 | 0.81 | TEAD1 (0.50) | TEAD1YAP1TLR2TLR1 | |
| SCHEMBL27255265 | 0.80 | TEAD1 (0.49) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL20767258 | 0.79 | TEAD1 (0.85) | TEAD1YAP1TNNI3KTLR2TLR1 | |
| SCHEMBL24496353 | 0.78 | TEAD1 (0.57) | TEAD1YAP1TNNI3KTLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542315-B | Benzosulfonyl compounds | 维瓦斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |