Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18588604 | 0.89 | PTGS1 (0.40) | PTGS1PTGS2FFAR4ACACBHRH3 | |
| SCHEMBL169750 | 0.88 | SYK (0.44) | PTGS1PTGS2FFAR4ACACBHRH3 | |
| SCHEMBL12311918 | 0.87 | HRH3 (0.51) | PTGS1PTGS2ACACBHRH3FPR2 | |
| SCHEMBL16483442 | 0.85 | HTR2C (0.46) | PTGS1PTGS2FFAR4ACACBHRH3 | |
| SCHEMBL8251445 | 0.84 | FFAR4 (0.38) | PTGS1PTGS2FFAR4ACACBHRH3 | |
| SCHEMBL3128358 | 0.84 | FFAR4 (0.38) | PTGS1PTGS2FFAR4HRH3FPR2 | |
| SCHEMBL3126765 | 0.84 | SLC6A2 (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17282339 | 0.82 | ACACB (0.44) | FFAR4ACACBHRH3 | |
| SCHEMBL18295347 | 0.82 | HTR2C (0.54) | SLC6A2 | |
| SCHEMBL24716435 | 0.82 | PTGS1 (0.46) | PTGS1PTGS2FFAR4ACACBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164250-A1 | SEC61 INHIBITORS AND USE THEREOF | KEZAR LIFE SCIENCES (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2019040104-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |