Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26503063 | 0.87 | HTR6 (0.50) | HTR6GAAMAPTPTGDR2CYP2A6 | |
| SCHEMBL20765211 | 0.86 | HTR6 (0.47) | HTR6GAAMAPTPTGDR2CYP2A6 | |
| SCHEMBL30380898 | 0.86 | HTR6 (0.47) | HTR6GAAMAPTPTGDR2CYP2A6 | |
| SCHEMBL4316470 | 0.86 | HTR6 (0.47) | HTR6GAAMAPTPTGDR2CYP2A6 | |
| SCHEMBL17105299 | 0.84 | HTR6 (0.45) | HTR6GAAMAPTPTGDR2CYP11B1 | |
| SCHEMBL30405579 | 0.81 | CYP2C19 (0.51) | HTR6GAAMAPTPTGDR2CYP2A6 | |
| SCHEMBL20765228 | 0.81 | HTR6 (0.43) | HTR6GAAMAPTPTGDR2CYP2A6 | |
| SCHEMBL20783101 | 0.81 | CYP17A1 (0.44) | HTR6MAPTPTGDR2PTGS2GBA1 | |
| SCHEMBL20782959 | 0.78 | PTGDR2 (0.42) | HTR6MAPTPTGDR2LATS1PIK3C3 | |
| SCHEMBL29941106 | 0.76 | CA12 (0.42) | HTR6MAPTPTGDR2PIK3C3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038384-A1 | AZAINDOLYLPYRIDONE AND DIAZAINDOLYLPYRIDONE COMPOUNDS | SPRINT BIOSCIENCE AB (SE) | 2019-02-28 | — | — | WO | disclosed |