Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 8/20 | 0.38 |
| ▸ | CHUK | O15111 | 8/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.36 |
| ▸ | CDK9 | P50750 | 4/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | CIT | O14578 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445796 | 0.82 | CCNK (0.38) | CCNKCDK12IKBKBCHUKPIK3C3 | |
| SCHEMBL20782954 | 0.82 | NPY5R (0.43) | CCNKCDK12PIK3C3CCNT1CDK9 | |
| SCHEMBL20783060 | 0.80 | PIK3C3 (0.53) | CCNKCDK12IKBKBCHUKPIK3C3 | |
| SCHEMBL20782950 | 0.74 | — | — | |
| SCHEMBL20782949 | 0.74 | PTGDR2 (0.35) | PIK3C3CCNT1CDK9 | |
| SCHEMBL20782506 | 0.72 | EGFR (0.40) | PIK3C3 | |
| SCHEMBL20783141 | 0.70 | PIK3C3 (0.54) | CCNKCDK12IKBKBCHUKPIK3C3 | |
| SCHEMBL20776120 | 0.70 | JAK2 (0.46) | IKBKBCHUKLRRK2 | |
| SCHEMBL20782372 | 0.69 | PIK3C3 (0.44) | PIK3C3AURKB | |
| SCHEMBL20765177 | 0.69 | PIK3C3 (0.67) | CCNKCDK12IKBKBCHUKPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038384-A1 | AZAINDOLYLPYRIDONE AND DIAZAINDOLYLPYRIDONE COMPOUNDS | SPRINT BIOSCIENCE AB (SE) | 2019-02-28 | — | — | WO | disclosed |