Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 8/20 | 0.36 |
| ▸ | CHUK | O15111 | 8/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.34 |
| ▸ | CIT | O14578 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445805 | 0.84 | PIK3C3 (0.41) | CCNKCDK12PIK3C3CCNT1CDK9 | |
| SCHEMBL20783137 | 0.82 | CCNK (0.40) | CCNKCDK12IKBKBCHUKPIK3C3 | |
| SCHEMBL24445749 | 0.82 | PIK3C3 (0.51) | CCNKCDK12IKBKBCHUKPIK3C3 | |
| SCHEMBL23891827 | 0.73 | PIK3C3 (0.52) | CCNKCDK12IKBKBCHUKPIK3C3 | |
| SCHEMBL24240604 | 0.72 | PIK3C3 (0.45) | PIK3C3 | |
| SCHEMBL24445799 | 0.72 | CDK9 (0.42) | IKBKBCHUKCCNT1CDK9 | |
| SCHEMBL23891876 | 0.70 | HTR6 (0.36) | PIK3C3 | |
| SCHEMBL24240607 | 0.69 | PGR (0.33) | — | |
| SCHEMBL24445800 | 0.69 | JAK2 (0.40) | CCNKCDK12IKBKBCHUKCDK9 | |
| SCHEMBL23891886 | 0.68 | TRPA1 (0.38) | ROCK1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001278-A1 | AZAINDOLYLPYRIDONE AND DIAZAINDOLYLPYRIDONE COMPOUNDS | Sprint Bioscience AB (SE) | 2022-05-25 | — | — | EP | disclosed |