Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072626 | 0.75 | MAPT (0.47) | ADORA1GPR119ALDH1A1KDM4EHPGD | |
| SCHEMBL2080390 | 0.75 | ADORA1 (0.46) | ADORA1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL2078299 | 0.74 | ADORA1 (0.39) | ADORA1ALDH1A1KDM4EGRM5SMN1; SMN2 | |
| SCHEMBL937489 | 0.73 | ADORA1 (0.85) | ADORA1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL23200226 | 0.72 | ADORA1 (0.53) | ADORA1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL7795815 | 0.71 | ADORA1 (0.69) | ADORA1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL23198536 | 0.71 | ADORA1 (0.49) | ADORA1LMNASMN1; SMN2MAPTATM | |
| SCHEMBL27302179 | 0.70 | ADORA1 (0.81) | ADORA1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL938054 | 0.70 | ADORA1 (1.00) | ADORA1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL23198540 | 0.69 | ADORA1 (0.48) | ADORA1ALDH1A1MEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897595-B2 | Pyridoazepine derivatives | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2011-03-01 | — | — | US | claimed |
| US-20070281918-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | US | claimed |
| US-7897595-B2 | Pyridoazepine derivatives | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2011-03-01 | — | — | US | disclosed |
| US-7897595-B2 | Pyridoazepine derivatives | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2011-03-01 | — | — | US | disclosed |
| US-7897595-B2 | Pyridoazepine derivatives | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2011-03-01 | — | — | US | disclosed |
| WO-2007140213-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007140213-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | WO | disclosed |
| US-20070281918-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | US | disclosed |
| US-20070281918-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | US | disclosed |
| US-20070281918-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281918-A1 | PYRIDOAZEPINE DERIVATIVES | HTR2C, HTR5A, HTR2A | ADORA1 91/4885GPR119 640/4885ALDH1A1 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.