SCHEMBL2078735

SCHEMBL2078735

Oc1cc(-c2ccccc2)c(Oc2ccccc2)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.61
PDE4A P27815 3/20 0.61
PDE4C Q08493 3/20 0.61
PDE4D Q08499 3/20 0.61
BACE1 P56817 2/20 0.50
GSTP1 P09211 1/20 0.41
ALOX5 P09917 1/20 0.40
TTR P02766 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
HSD17B10 Q99714 1/20 0.39
LTA4H P09960 2/20 0.38
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4369722 0.92 PDE4B (0.54) PDE4BPDE4APDE4CPDE4DBACE1
Pyrophosphoric Acid SCHEMBL1900204 0.89 PDE4B (0.50) PDE4BPDE4APDE4CPDE4DBACE1
Pyrophosphoric Acid SCHEMBL3446718 0.79 PDE4B (0.47) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL28036379 0.79 PDE4B (0.53) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL11210849 0.78 BACE1 (0.48) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL983374 0.77 PDE4B (0.46) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL49711 0.76 BACE1 (0.60) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL27696698 0.76 NCOA1 (0.45) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL21382004 0.75 BACE1 (0.65) PDE4BPDE4APDE4CPDE4DBACE1
SCHEMBL1760415 0.74 PDE4B (0.62) PDE4BPDE4APDE4CPDE4DBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163864-B2 Sulfonated polyarylene compounds, membrane material made therefrom, method for the production thereof and use LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2012-04-24 US claimed
US-20110172317-A1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF AND USE LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2011-07-14 US claimed
EP-2046491-B1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE LEIBNIZ INST POLYMERFORSCHUNG (DE) 2010-05-12 EP claimed
US-8163864-B2 Sulfonated polyarylene compounds, membrane material made therefrom, method for the production thereof and use LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2012-04-24 US disclosed
US-20110172317-A1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF AND USE LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2011-07-14 US disclosed
US-6881811-B2 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20040147710-A1 Improved heat resistance and low relative permittivity; insulating films for electronic devices/multilayerd wiring boards ASAHI GLASS COMPANY LIMITED (JP) 2004-07-29 US disclosed