Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | HPN | P05981 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076733 | 0.92 | CHRM3 (0.34) | CTSK | |
| SCHEMBL22076736 | 0.92 | CHRM3 (0.34) | CTSK | |
| SCHEMBL22076735 | 0.92 | CHRM3 (0.34) | CTSK | |
| SCHEMBL20786873 | 0.85 | PLAU (0.40) | PLAUHPNHDAC8HDAC3HDAC4 | |
| SCHEMBL20786875 | 0.85 | PLAU (0.40) | PLAUHPNHDAC8HDAC3HDAC4 | |
| SCHEMBL20788693 | 0.85 | NPC1 (0.39) | PLAUHPNHDAC8HDAC3HDAC4 | |
| SCHEMBL20787628 | 0.84 | MEN1 (0.41) | PLAUHPNHDAC8HDAC3HDAC4 | |
| SCHEMBL20787469 | 0.81 | PLAU (0.40) | PLAUHPNMAPK1LMNAMEN1 | |
| SCHEMBL20764481 | 0.78 | MEN1 (0.44) | PLAUHDAC8HDAC3HDAC1HDAC2 | |
| SCHEMBL20764482 | 0.78 | MEN1 (0.44) | PLAUHDAC8HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |