Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 6/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076735 | 1.00 | CHRM3 (0.34) | CHRM3CHRM2DPP4EHMT2EHMT1 | |
| SCHEMBL22076733 | 1.00 | CHRM3 (0.34) | CHRM3CHRM2DPP4EHMT2EHMT1 | |
| SCHEMBL20787632 | 0.92 | PLAU (0.35) | CTSK | |
| SCHEMBL22076715 | 0.86 | CHRM3 (0.39) | CHRM3CHRM2DPP4EHMT2 | |
| SCHEMBL22076707 | 0.86 | CHRM3 (0.39) | CHRM3CHRM2DPP4EHMT2 | |
| SCHEMBL20764547 | 0.85 | MMP2 (0.37) | CHRM3CHRM2DPP4 | |
| SCHEMBL20764544 | 0.85 | MMP2 (0.37) | CHRM3CHRM2DPP4 | |
| SCHEMBL20764474 | 0.84 | MMP2 (0.37) | CHRM3CHRM2DPP4 | |
| SCHEMBL20764587 | 0.84 | MMP2 (0.35) | CHRM3CHRM2DPP4 | |
| SCHEMBL20764471 | 0.84 | MMP2 (0.37) | CHRM3CHRM2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034648-B2 | Cystobactamide derivatives | HELMHOLTZ-ZENTRUM FÜR (DE) | 2021-06-15 | — | — | US | disclosed |
| US-20200190020-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034648-B2 | Cystobactamide derivatives | CTH, CBS, SLC7A11 | CHRM3 3381/4885CHRM2 2888/4885DPP4 1682/4885 |
| US-20200190020-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | CTH, CBS, SLC7A11 | CHRM3 4187/4885CHRM2 3775/4885DPP4 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.