Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 4/20 | 0.41 |
| ▸ | NADK | O95544 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | FHIT | P49789 | 1/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20792565 | 0.91 | POLB (0.40) | POLBENPP1P2RY1NT5EDTYMK | |
| SCHEMBL22219944 | 0.83 | POLB (0.51) | POLBENPP1P2RY1NT5EDTYMK | |
| SCHEMBL22219942 | 0.83 | POLB (0.44) | POLBENPP1P2RY1NT5EDTYMK | |
| SCHEMBL22220040 | 0.82 | POLB (0.40) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL20792516 | 0.79 | RNASEL (0.51) | DTYMKNADK | |
| SCHEMBL22219781 | 0.79 | RNASEL (0.46) | POLBENPP1P2RY1NT5EDTYMK | |
| SCHEMBL22220038 | 0.76 | NT5E (0.40) | P2RY1NT5ENADKIMPDH2FHIT | |
| SCHEMBL22220036 | 0.76 | NT5E (0.40) | P2RY1NT5ENADKIMPDH2FHIT | |
| SCHEMBL22220033 | 0.75 | POLB (0.42) | POLBENPP1P2RY1FHITDNPH1 | |
| SCHEMBL22080569 | 0.75 | STING1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019046498-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |