Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 10/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460128 | 0.80 | ENPP1 (0.48) | ENPP1P2RY2P2RY6P2RY4POLA1 | |
| SCHEMBL309522 | 0.77 | ENPP1 (0.49) | ENPP1P2RY2P2RY6P2RY4POLA1 | |
| SCHEMBL20541413 | 0.76 | TYMP (0.40) | POLA1 | |
| SCHEMBL7743090 | 0.74 | POLG (0.40) | P2RY2P2RY6P2RY4 | |
| SCHEMBL5583926 | 0.73 | CRBN (0.42) | ENPP1 | |
| SCHEMBL1433847 | 0.73 | ENPP1 (0.46) | ENPP1P2RY2P2RY6P2RY4 | |
| Triphosphate SCHEMBL869856 | 0.71 | ENPP1 (0.51) | ENPP1P2RY2P2RY6P2RY4POLA1 | |
| SCHEMBL27883978 | 0.66 | CRBN (0.45) | — | |
| SCHEMBL11666542 | 0.65 | CRBN (0.52) | — | |
| SCHEMBL572752 | 0.62 | CRBN (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277649-A1 | BROAD SPECTRUM DETECTION OF DNA DAMAGE BY REPAIR ASSISTED DAMAGE DETECTION (RADD) | RAMOT AT TEL AVIV UNIVERSITY, LTD (IL) | 2020-09-03 | — | — | US | claimed |
| WO-2019051043-A1 | BROAD SPECTRUM DETECTION OF DNA DAMAGE BY REPAIR ASSISTED DAMAGE DETECTION (RADD) | UNIVERSITY OF SOUTH ALABAMA (US) | 2019-03-14 | — | — | WO | claimed |
| WO-2023196983-A2 | METHODS FOR POLYNUCLEOTIDE SEQUENCING | Singular Genomics Systems, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20200277649-A1 | BROAD SPECTRUM DETECTION OF DNA DAMAGE BY REPAIR ASSISTED DAMAGE DETECTION (RADD) | RAMOT AT TEL AVIV UNIVERSITY, LTD (IL) | 2020-09-03 | — | — | US | disclosed |
| WO-2019051043-A1 | BROAD SPECTRUM DETECTION OF DNA DAMAGE BY REPAIR ASSISTED DAMAGE DETECTION (RADD) | UNIVERSITY OF SOUTH ALABAMA (US) | 2019-03-14 | — | — | WO | disclosed |