Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28220162 | 0.86 | CRBN (0.45) | ENPP1P2RY2P2RY4P2RY6 | |
| Water SCHEMBL28246784 | 0.78 | CRBN (0.52) | — | |
| SCHEMBL7650207 | 0.78 | CRBN (0.52) | — | |
| SCHEMBL309522 | 0.78 | ENPP1 (0.49) | ENPP1P2RY2POLA1P2RY4P2RY6 | |
| SCHEMBL460128 | 0.77 | ENPP1 (0.48) | ENPP1P2RY2POLA1P2RY4P2RY6 | |
| Benzene SCHEMBL26606841 | 0.77 | CRBN (0.55) | — | |
| SCHEMBL20798160 | 0.71 | ENPP1 (0.43) | ENPP1P2RY2POLA1P2RY4P2RY6 | |
| SCHEMBL6515465 | 0.70 | CRBN (0.44) | — | |
| Furan SCHEMBL1628664 | 0.69 | CRBN (0.43) | — | |
| SCHEMBL1433847 | 0.69 | ENPP1 (0.46) | ENPP1P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120078529-A1 | DETERMINING THE SEVERITY OF 5-FLUOROURACIL OVERDOSE | WELLSTAT THERAPEUTICS CORPORATION (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2010132434-A1 | DETERMINING THE SEVERITY OF 5-FLUOROURACIL OVERDOSE | WELLSTAT THERAPEUTICS CORPORATION (US) | 2010-11-18 | — | — | WO | disclosed |