SCHEMBL20798271

SCHEMBL20798271

NC(=O)C1C(F)C12CCCCC2F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672289 0.67 EPHX1 (0.33) EPHX1
SCHEMBL23795633 0.63
SCHEMBL3986262 0.62 UGT2B7 (0.40) EPHX1
SCHEMBL15542158 0.60 EPHX1 (0.34) EPHX1
SCHEMBL15542322 0.60 EPHX1 (0.34) EPHX1
SCHEMBL4612910 0.60 GRM2 (0.32)
SCHEMBL3725259 0.60 EPHX1 (0.30) EPHX1
SCHEMBL16738225 0.60 EPHX1 (0.34) EPHX1
SCHEMBL27991277 0.60 LMNA (0.32)
Hydrochloric Acid SCHEMBL15542389 0.59 EPHX1 (0.33) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019051396-A1 SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2019-03-14 WO disclosed