Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 12/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079851 | 1.00 | PTGES (0.34) | PTGES | |
| SCHEMBL2078009 | 0.86 | PTGES (0.33) | PTGES | |
| SCHEMBL2078006 | 0.86 | PTGES (0.33) | PTGES | |
| SCHEMBL925423 | 0.84 | MEN1 (0.35) | — | |
| SCHEMBL925425 | 0.84 | MEN1 (0.35) | — | |
| SCHEMBL2175743 | 0.84 | SLC1A1 (0.37) | — | |
| SCHEMBL4356102 | 0.81 | PTGES (0.34) | PTGES | |
| SCHEMBL4356095 | 0.81 | PTGES (0.34) | PTGES | |
| SCHEMBL925382 | 0.75 | MEN1 (0.34) | — | |
| SCHEMBL925385 | 0.75 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163909-B2 | Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use | AMGEN INC. (US) | 2012-04-24 | — | — | US | disclosed |