Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918648 | 0.82 | HTT (0.50) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL7915297 | 0.81 | KMT2A (0.47) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL3071598 | 0.79 | GAA (0.80) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL20799602 | 0.79 | CASR (0.53) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL20799618 | 0.78 | KMT2A (0.42) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL20323996 | 0.75 | KMT2A (0.54) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL16281760 | 0.74 | FPR2 (0.56) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL16281745 | 0.74 | FPR2 (0.56) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL3090261 | 0.73 | KMT2A (0.56) | KMT2AMEN1MAPTHTTALDH1A1 | |
| SCHEMBL16281759 | 0.73 | ANPEP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2811295-B1 | SEPARATING AGENT AND METHOD FOR MANUFACTURING SAME | SHISEIDO CO LTD (JP) | 2019-03-13 | — | — | EP | disclosed |