⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522121 | 0.80 | HCAR2 (0.70) | — | |
| SCHEMBL185925 | 0.78 | — | — | |
| SCHEMBL9210101 | 0.78 | — | — | |
| Pyridazine SCHEMBL19535239 | 0.77 | HCAR2 (0.87) | — | |
| SCHEMBL1416725 | 0.76 | — | — | |
| SCHEMBL29024213 | 0.76 | — | — | |
| SCHEMBL7439626 | 0.76 | — | — | |
| SCHEMBL2896973 | 0.76 | — | — | |
| SCHEMBL2007577 | 0.76 | — | — | |
| SCHEMBL28549559 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101888780-B | Quinolone analogs and methods related thereto | CYLENE PHARMACEUTICALS INC | 2014-08-13 | — | — | CN | disclosed |
| US-8338362-B2 | Methods for controlling SR protein phosphorylation, and antiviral agents whose active ingredients comprise agents that control SR protein activity | MASATOSHI HAGIWARA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-8338362-B2 | Methods for controlling SR protein phosphorylation, and antiviral agents whose active ingredients comprise agents that control SR protein activity | MASATOSHI HAGIWARA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100016359-A1 | METHODS FOR CONTROLLING SR PROTEIN PHOSPHORYLATION, AND ANTIVIRAL AGENTS WHOSE ACTIVE INGREDIENTS COMPRISE AGENTS THAT CONTROL SR PROTEIN ACTIVITY | MASATOSHI HAGIWARA | 2010-01-21 | — | — | US | disclosed |
| US-20100016359-A1 | METHODS FOR CONTROLLING SR PROTEIN PHOSPHORYLATION, AND ANTIVIRAL AGENTS WHOSE ACTIVE INGREDIENTS COMPRISE AGENTS THAT CONTROL SR PROTEIN ACTIVITY | MASATOSHI HAGIWARA | 2010-01-21 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-0718277-B1 | Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound | FUJI PHOTO FILM CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0718277-A1 | Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound | FUJI PHOTO FILM CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |