Pyridazine

Pyridazine

SCHEMBL19535239

O=C(O)c1ccnnc1.c1ccnnc1

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.87
ALDH1A1 P00352 2/20 0.52
APP P05067 1/20 0.52
GAA P10253 1/20 0.52
HCAR3 P49019 1/20 0.52
NAPRT Q6XQN6 3/20 0.48
P4HA1 P13674 3/20 0.43
P4HTM Q9NXG6 2/20 0.43
KDM4E B2RXH2 2/20 0.43
KDM6B O15054 2/20 0.43
KDM4A O75164 2/20 0.43
KDM5C P41229 2/20 0.43
KDM4C Q9H3R0 2/20 0.43
KDM2A Q9Y2K7 2/20 0.43
KDM3A Q9Y4C1 2/20 0.43
TSHR P16473 2/20 0.42
DAO P14920 1/20 0.42
TBXA2R P21731 4/20 0.42
TBXAS1 P24557 3/20 0.42
MIF P14174 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185925 0.93
SCHEMBL28011427 0.91 HCAR2 (0.95) HCAR2ALDH1A1APPGAAHCAR3
Trifluoroacetic Acid SCHEMBL30226472 0.82 HCAR2 (0.77) HCAR2ALDH1A1APPGAAHCAR3
Benzoic Acid SCHEMBL8611265 0.79 NAPRT (0.70) HCAR2ALDH1A1APPGAAHCAR3
Niacin SCHEMBL28154059 0.79 ALDH1A1 (0.84) HCAR2ALDH1A1APPGAAHCAR3
Dimethylformamide SCHEMBL27769808 0.79 HCAR2 (0.71) HCAR2ALDH1A1APPGAAHCAR3
SCHEMBL2080002 0.77
SCHEMBL1987189 0.77 KMT2A (0.63) HCAR2ALDH1A1TBXA2RTBXAS1MAPT
SCHEMBL31522121 0.77 HCAR2 (0.70) HCAR2ALDH1A1NAPRTTBXA2RTBXAS1
Pyrazinoic Acid SCHEMBL22409664 0.76 HCAR2 (0.67) HCAR2ALDH1A1APPGAAHCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812315-B2 Treating solution for electronic parts, and process for producing electronic parts FINE POLYMERS CORPORATION (JP) 2017-11-07 US disclosed