Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | OTC | P00480 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 6/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.42 |
| ▸ | NOS3 | P29474 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512847 | 0.89 | SLC1A3 (0.42) | GSRKMT2ACYP1A2 | |
| SCHEMBL29604004 | 0.87 | GSR (0.47) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL7702029 | 0.85 | GSR (0.52) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL14199857 | 0.82 | GSR (0.50) | GSRNOS2NOS1NOS3CYP2C19 | |
| SCHEMBL10583206 | 0.79 | GSR (0.55) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL13005399 | 0.79 | GSR (0.55) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL13067630 | 0.78 | GSR (0.46) | GSRNOS2NOS1NOS3ARG2 | |
| SCHEMBL10286393 | 0.78 | NOD1 (0.51) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL13176535 | 0.78 | GSR (0.48) | GSROTCNOS2NOS1NOS3 | |
| SCHEMBL10286394 | 0.78 | NOD1 (0.51) | GSROTCNOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225248-B1 | MODIFIED BOVINE G-CSF POLYPEPTIDES AND THEIR USES | AMBRX INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-2858676-B1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATES | AMBRX INC (US) | 2019-03-13 | — | — | EP | disclosed |