SCHEMBL20801149

SCHEMBL20801149

CSc1ccc(N(C)c2ccc(Oc3nc(O)c4ccncc4n3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20801154 0.90 KDM4C (0.49) KDM4C
SCHEMBL17602153 0.89 KDM4C (0.58) KDM4C
SCHEMBL17602231 0.87 KDM4C (0.59) KDM4C
SCHEMBL17602069 0.87 KDM4C (0.59) KDM4C
SCHEMBL17602149 0.87 KDM4C (0.59) KDM4C
SCHEMBL17615564 0.86 KDM4C (0.48) KDM4C
SCHEMBL17602348 0.86 KDM4C (0.60) KDM4C
SCHEMBL17503832 0.85 KDM4C (0.53) KDM4C
SCHEMBL24166654 0.84 KDM4C (0.51) KDM4C
SCHEMBL17602117 0.84 KDM4C (0.61) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3193601-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-01-05 EP disclosed
EP-3453710-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2019-03-13 EP disclosed