SCHEMBL20801154

SCHEMBL20801154

CSc1cccc(N(C)c2ccc(Oc3nc(O)c4ccncc4n3)cc2)c1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20801149 0.90 KDM4C (0.47) KDM4C
SCHEMBL17602169 0.88 KDM4C (0.63) KDM4C
SCHEMBL29542008 0.87 KDM4C (0.63) KDM4C
SCHEMBL17602341 0.87 KDM4C (0.52) KDM4C
SCHEMBL17602147 0.87 KDM4C (0.63) KDM4C
SCHEMBL17602231 0.86 KDM4C (0.59) KDM4C
SCHEMBL17602267 0.86 KDM4C (0.64) KDM4C
SCHEMBL17602086 0.86 KDM4C (0.64) KDM4C
SCHEMBL29542124 0.84 KDM4C (0.65) KDM4C
SCHEMBL17602372 0.84 KDM4C (0.65) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3193601-B1 HISTONE DEMETHYLASE INHIBITORS CELGENE QUANTICEL RES INC (US) 2022-01-05 EP disclosed
EP-3453710-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2019-03-13 EP disclosed