Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 18/20 | 0.48 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898316 | 0.82 | KDM4C (0.55) | KDM4C | |
| SCHEMBL19268160 | 0.75 | KDM4C (0.42) | KDM4C | |
| SCHEMBL17602383 | 0.74 | KDM4C (0.70) | KDM4C | |
| SCHEMBL22163336 | 0.73 | KDM4C (0.50) | KDM4C | |
| SCHEMBL17602072 | 0.72 | KDM4C (0.66) | KDM4C | |
| SCHEMBL19268161 | 0.70 | LATS1 (0.42) | KDM4CLATS1 | |
| SCHEMBL17602071 | 0.69 | KDM4C (0.67) | KDM4C | |
| SCHEMBL20724154 | 0.69 | KDM4C (0.55) | KDM4C | |
| SCHEMBL19268158 | 0.69 | EGFR (0.43) | KDM4C | |
| SCHEMBL20801150 | 0.68 | KDM4C (0.64) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453710-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2019-03-13 | — | — | EP | disclosed |