⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181107 | 0.98 | — | — | |
| SCHEMBL20801501 | 0.98 | — | — | |
| SCHEMBL24859936 | 0.98 | — | — | |
| SCHEMBL20801421 | 0.88 | — | — | |
| SCHEMBL23813737 | 0.83 | CAMK2A (0.32) | — | |
| SCHEMBL20801579 | 0.83 | CAMK2A (0.32) | — | |
| SCHEMBL20801584 | 0.81 | PSMB8 (0.33) | — | |
| SCHEMBL22180988 | 0.81 | — | — | |
| SCHEMBL20801353 | 0.81 | — | — | |
| SCHEMBL20801357 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284750-A1 | Immunoconjugate Synthesis Method | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| US-10675358-B2 | Antibody adjuvant conjugates | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190076547-A1 | ANTIBODY ADJUVANT CONJUGATES | BOLT BIOTHERAPEUTICS, INC. | 2019-03-14 | — | — | US | disclosed |