⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20801357 | 1.00 | — | — | |
| SCHEMBL20801353 | 1.00 | — | — | |
| SCHEMBL20801421 | 0.90 | — | — | |
| SCHEMBL22038805 | 0.89 | — | — | |
| SCHEMBL22549366 | 0.89 | — | — | |
| SCHEMBL23813737 | 0.87 | CAMK2A (0.32) | — | |
| SCHEMBL20801579 | 0.87 | CAMK2A (0.32) | — | |
| SCHEMBL20801483 | 0.86 | NAAA (0.34) | — | |
| SCHEMBL23813716 | 0.83 | NPC1 (0.35) | — | |
| SCHEMBL23813720 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11110178-B2 | Antibody adjuvant conjugates | THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (US) | 2021-09-07 | — | — | US | disclosed |
| US-20200206357-A1 | ANTIBODY ADJUVANT CONJUGATES | BOLT BIOTHERAPEUTICS, INC. | 2020-07-02 | — | — | US | disclosed |