Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394294 | 1.00 | PPM1D (0.33) | PPM1D | |
| SCHEMBL140873 | 0.88 | PPM1D (0.33) | PPM1D | |
| SCHEMBL2386709 | 0.85 | PPM1D (0.35) | PPM1D | |
| SCHEMBL142690 | 0.85 | PPM1D (0.35) | PPM1D | |
| SCHEMBL139881 | 0.85 | PPM1D (0.35) | PPM1D | |
| SCHEMBL2387182 | 0.82 | PPM1D (0.34) | PPM1D | |
| SCHEMBL28037304 | 0.82 | PPM1D (0.34) | PPM1D | |
| SCHEMBL16538825 | 0.81 | PPM1D (0.33) | PPM1D | |
| SCHEMBL2081002 | 0.79 | PPM1D (0.32) | PPM1D | |
| SCHEMBL27224277 | 0.78 | PPM1D (0.32) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906532-B2 | Antiserotonine agents; gastrointestinal disorders; irritable bowel syndrome; central nervous system disorders; Alzheimer's disease; cognition activators; analgesics; cardiovascular disorders; antidiabetic agents; sleep disorders | PFIZER INC. (US) | 2011-03-15 | — | — | US | disclosed |