Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 19/20 | 0.78 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.78 |
| ▸ | BPTF | Q12830 | 3/20 | 0.60 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.60 |
| ▸ | BRD1 | O95696 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.60 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.60 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.60 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718084 | 0.88 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL23682875 | 0.88 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL17912355 | 0.88 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL25049813 | 0.88 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL17916738 | 0.88 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL30830640 | 0.80 | KAT2B (0.77) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL30830497 | 0.80 | KAT2B (0.77) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL30830592 | 0.79 | KAT2B (0.79) | KAT2BBRD9BPTFKAT2ABRD1 | |
| SCHEMBL17916739 | 0.76 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2A | |
| SCHEMBL17916737 | 0.76 | KAT2B (1.00) | KAT2BBRD9BPTFKAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076542-A1 | C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076542-A1 | C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | STUB1, UBE3C, UBE3A | KAT2B 4197/4885BRD9 2815/4885BPTF 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.