Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.75 |
| ▸ | FGFR2 | P21802 | 20/20 | 0.75 |
| ▸ | FGFR4 | P22455 | 20/20 | 0.75 |
| ▸ | FGFR3 | P22607 | 20/20 | 0.75 |
| ▸ | KDR | P35968 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20808369 | 0.91 | FGFR1 (0.75) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL20808262 | 0.88 | FGFR4 (0.75) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL20808255 | 0.87 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905439 | 0.86 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL20808368 | 0.85 | FGFR1 (0.66) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905566 | 0.84 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905576 | 0.81 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL18768880 | 0.79 | FGFR1 (0.75) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL21128376 | 0.79 | FGFR1 (0.65) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL14905234 | 0.79 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776436-B1 | NEW COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2019-03-13 | — | — | EP | disclosed |