Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24449562 | 0.85 | MAPT (0.51) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL17816030 | 0.83 | MAPT (0.43) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL4494836 | 0.83 | MAPT (0.45) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL21025175 | 0.82 | MAPT (0.40) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL22060169 | 0.79 | HSD17B10 (0.38) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL18059328 | 0.77 | CHRNB2 (0.45) | MAPTMEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL20082948 | 0.76 | CHRNB2 (0.50) | MAPTCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL23338433 | 0.76 | HSD17B10 (0.44) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL24449477 | 0.76 | MAPT (0.38) | MAPTGAAHSD17B10MEN1KMT2A | |
| SCHEMBL24744499 | 0.75 | CHRNB2 (0.53) | MAPTMEN1KMT2ACHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453707-B1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2022-02-16 | — | — | EP | disclosed |
| EP-3453707-A1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2019-03-13 | — | — | EP | disclosed |