Pentachlorophenol

Pentachlorophenol

SCHEMBL20812

CC(=O)O.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Pentachlorophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.62
HPGD P15428 5/20 0.62
HSD17B10 Q99714 5/20 0.62
MEN1 O00255 2/20 0.62
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62
MAPT P10636 2/20 0.62
KMT2A Q03164 2/20 0.62
CYP1A2 P05177 4/20 0.46
CYP2C9 P11712 4/20 0.46
CYP2C19 P33261 1/20 0.46
FFAR3 O14843 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
HIF1A Q16665 3/20 0.40
MAPK1 P28482 3/20 0.39
CYP3A4 P08684 2/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL2531328 0.97 TSHR (0.59) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL8497787 0.97 TSHR (0.59) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL5859188 0.97 TSHR (0.59) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL11109917 0.92 TSHR (0.53) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL7801029 0.90 TSHR (0.67) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL28343301 0.87 HPGD (0.71) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL17595225 0.84 TSHR (0.50) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL6876934 0.83 TSHR (0.43) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL15212565 0.83 HSD17B10 (0.91) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL29079536 0.82 TSHR (0.56) TSHRHPGDHSD17B10MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2551 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4375325-A2 BIOCIDAL RESIN COMPOSITION INCLUDING ONE OR A PLURALITY OF RESINS SELECTED FROM MF, UF, PF, MUF AND PHENOLIC RESINS; AND MORE THAN ONE SOLUBLE COPPER SALT COPPTECH UK LTD. (CL) 2024-05-29 EP claimed
WO-2024089069-A2 DETERGENTS AND CLEANING COMPOSITIONS WITH STABILIZED ENZYME SYMRISE AG (DE) 2024-05-02 WO claimed
US-20240042065-A1 THERANOSTIC AGENTS SATHIYAJITH CUHAWIJAY (AU) 2024-02-08 US claimed
US-20240002905-A1 PATHOGEN INACTIVATING AND NUCLEIC ACID STABILIZATION MEDIA FOR MICROORGANISM COLLECTION AND TRANSPORT BIOCEPT, INC. (US) 2024-01-04 US claimed
EP-4288111-A1 MULTIPURPOSE COMPOSITIONS FOR COLLECTING AND TRANSPORTING BIOLOGICAL MATERIAL Longhorn Vaccines and Diagnostics, LLC (US) 2023-12-13 EP claimed
EP-4288411-A1 SOLUBLE CHELATOR FOR TARGETING RECOMBINANT PROTEINS Cube Biotech GmbH (DE) 2023-12-13 EP claimed
CN-116818957-B Method for detecting content of sodium pentachlorophenolic acid and metabolite thereof in live pig sample 中国农业科学院农业质量标准与检测技术研究所 2023-11-14 CN claimed
CN-116818957-A Method for detecting content of sodium pentachlorophenolic acid and metabolite thereof in live pig sample 中国农业科学院农业质量标准与检测技术研究所 2023-09-29 CN claimed
EP-4244236-A1 PATHOGEN INACTIVATING AND NUCLEIC ACID STABILIZATION MEDIA FOR MICROORGANISM COLLECTION AND TRANSPORT Biocept, Inc. (US) 2023-09-20 EP claimed
WO-2023152112-A1 DRY COMPOSITIONS AND METHODS FOR FORMING STABLE LIQUID CLEANSING FORMULATIONS UNILEVER IP HOLDINGS B.V. (NL) 2023-08-17 WO claimed
EP-0774688-A1 Method of processing a colour photographic silver halide material KODAK LIMITED (GB) 1997-05-21 EP claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
WO-1996026999-A1 LAUNDRY PRETREATMENT WITH PEROXIDE BLEACHES CONTAINING CHELATORS FOR IRON, COPPER OR MANGANESE FOR REDUCED FABRIC DAMAGE THE PROCTER & GAMBLE COMPANY (US) 1996-09-06 WO claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0504183-B1 POWDER COATINGS BASED ON EPOXY RESINS SWAN THOMAS & CO LTD (GB) 1994-08-17 EP claimed
US-5322644-A Dissolving contaminants in dilute basic chelating agent containing carbonate solution, separating, recovering by adsorption on anion exchange material BRADTEC-US, INC. (US) 1994-06-21 US claimed
EP-0504183-A1 POWDER COATINGS BASED ON EPOXY RESINS. SWAN THOMAS & CO LTD (GB) 1992-09-23 EP claimed
US-5030658-A For plant protection; sodium or potassium salts of oleic acid, linoleic acid and 12-20 carbon fatty acids; alkali metal or alkanolamine salt of carboxylic acids or alkylenepolyamine polyacidic acids as chelating agent SAFER, INC. (US) 1991-07-09 US claimed
WO-1991008268-A1 POWDER COATINGS BASED ON EPOXY RESINS THOMAS SWAN & CO., LTD. (GB) 1991-06-13 WO claimed
EP-0237075-A2 Prespotter laundry detergent S.C. JOHNSON & SON, INC. (US) 1987-09-16 EP claimed