Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ASGR1 | P07306 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539503 | 0.76 | TYR (0.36) | THRBCA1CA2CA9 | |
| SCHEMBL2040405 | 0.76 | TYR (0.36) | THRBCA1CA2CA9 | |
| SCHEMBL2040409 | 0.76 | TYR (0.36) | THRBCA1CA2CA9 | |
| SCHEMBL2040806 | 0.76 | TYR (0.36) | THRBCA1CA2CA9 | |
| SCHEMBL14536630 | 0.76 | TYR (0.36) | THRBCA1CA2CA9 | |
| SCHEMBL22461921 | 0.75 | ALDH1A1 (0.35) | MAPK1ASGR1ALDH1A1THRBCD69 | |
| SCHEMBL15333982 | 0.75 | ASGR1 (0.39) | MAPK1ASGR1CD69CA1CA2 | |
| SCHEMBL30400153 | 0.75 | ASGR1 (0.39) | MAPK1ASGR1CD69CA1CA2 | |
| SCHEMBL468788 | 0.75 | ASGR1 (0.39) | MAPK1ASGR1CD69CA1CA2 | |
| SCHEMBL468787 | 0.75 | ASGR1 (0.39) | MAPK1ASGR1CD69CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019051257-A2 | METHODS FOR TREATING HEPATITIS B INFECTIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-03-14 | — | — | WO | disclosed |