Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2081400 | 1.00 | TAAR1 (0.52) | TAAR1LTC4S | |
| SCHEMBL2081964 | 0.92 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL2081963 | 0.92 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL2079030 | 0.92 | TAAR1 (0.52) | TAAR1LTC4S | |
| SCHEMBL2079027 | 0.92 | TAAR1 (0.52) | TAAR1LTC4S | |
| SCHEMBL2081488 | 0.87 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL2083749 | 0.87 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL2081492 | 0.87 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL2080160 | 0.86 | TAAR1 (0.65) | TAAR1 | |
| SCHEMBL2079762 | 0.86 | TAAR1 (0.65) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121641-B1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | HOFFMANN LA ROCHE (CH) | 2014-09-24 | — | — | EP | disclosed |
| US-7902238-B2 | 2-aminooxazolines as TAAR1 ligands | HOFFMANN-LA ROCHE INC. (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090105307-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105307-A1 | 2-AMINOOXAZOLINES AS TAAR1 LIGANDS | TAAR1, TAAR5, NPSR1 | TAAR1 1/4885LTC4S 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.