Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685658 | 0.91 | CYP19A1 (0.44) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL1685668 | 0.88 | EPHX1 (0.44) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL1685653 | 0.85 | EPHX1 (0.41) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL2127574 | 0.83 | EPHX1 (0.47) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL1685632 | 0.81 | ALDH1A1 (0.49) | CYP19A1ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL293856 | 0.80 | EPHX1 (0.44) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL49247 | 0.80 | CYP19A1 (0.57) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL7642694 | 0.78 | EPHX1 (0.52) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL2128363 | 0.77 | EPHX1 (0.51) | CYP19A1EPHX1ALDH1A1MAPTHPGD | |
| SCHEMBL6412808 | 0.76 | ALDH1A1 (0.47) | CYP19A1ALDH1A1MAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341042-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2019-03-20 | — | — | EP | disclosed |