Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 10/20 | 0.48 |
| ▸ | PTGIR | P43119 | 10/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20815466 | 1.00 | PTGER2 (0.48) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20991869 | 0.91 | PTGER2 (0.42) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815451 | 0.87 | PTGIR (0.63) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815452 | 0.87 | PTGIR (0.63) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815486 | 0.83 | PTGIR (0.46) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815484 | 0.83 | PTGIR (0.46) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815475 | 0.80 | PTGIR (0.46) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815474 | 0.80 | PTGIR (0.46) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL20815456 | 0.79 | PTGIR (0.62) | PTGER2PTGIRPTGER4TSHRABCC4 | |
| SCHEMBL11459358 | 0.79 | PTGIR (0.62) | PTGER2PTGIRPTGER4TSHRABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071427-B | Novel prostaglandin derivative | ＡＧＣ株式会社 | 2024-08-20 | — | — | CN | disclosed |
| EP-3456710-B1 | NOVEL PROSTAGLANDIN DERIVATIVE | AGC INC (JP) | 2021-06-30 | — | — | EP | disclosed |
| US-10494338-B2 | Prostaglandin derivative | AGC Inc. (JP) | 2019-12-03 | — | — | US | disclosed |
| US-10494338-B2 | Prostaglandin derivative | AGC Inc. (JP) | 2019-12-03 | — | — | US | disclosed |
| US-20190135743-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2019-05-09 | — | — | US | disclosed |
| US-20190135743-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | AGC Inc. (JP) | 2019-05-09 | — | — | US | disclosed |
| EP-3456710-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | AGC INC. (JP) | 2019-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10494338-B2 | Prostaglandin derivative | PTGIR, PTGIS, PTGS1 | PTGER2 10/4885PTGIR 1/4885PTGER4 7/4885 |
| US-20190135743-A1 | NOVEL PROSTAGLANDIN DERIVATIVE | PTGIR, PTGIS, PTGER1 | PTGER2 9/4885PTGIR 1/4885PTGER4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.